What is one of the post-renal causes of AKI?

The identification of bladder rupture as a post-renal cause of acute kidney injury (AKI) is grounded in the understanding of how urine flow obstruction leads to kidney function impairment. In this case, the bladder rupture can cause urine to leak into the abdominal cavity or surrounding tissues, resulting in an obstruction of urinary outflow. This obstruction increases pressure within the urinary system, leading to retrograde pressure on the kidneys, which can severely compromise their function and ultimately result in AKI.

Post-renal causes of AKI are primarily associated with obstructions in the urinary tract, which interferes with normal urine drainage. In this context, bladder rupture fits this category perfectly as it directly disrupts the pathway for urine excretion. By hindering urine flow, it creates a scenario where the kidneys cannot effectively eliminate waste products from the bloodstream, leading to potential kidney damage. This demonstrates the critical link between urinary tract obstruction and the development of AKI.